Neobythites multiocellatus differs from the other eight West Atlantic Neobythites species by having 3 (rarely 4) ocelli on the dorsal fin, the anterior of which is placed somewhat behind a line through the origin of the anal fin, and by the following combination of characters: 0–1(weak) spine on hind margin of preopercle, total number of vertebrae 54–59, dorsal fin rays 94–101, anal fin rays 79–90 (Ref. 82372).